Metabolic stability of 3-Epi-1α,25-dihydroxyvitamin D3over 1α, 25-dihydroxyvitamin D3: Metabolism and molecular docking studies using rat CYP24A1-Reference-Cited by-同舟云学术

Metabolic stability of 3-Epi-1α,25-dihydroxyvitamin D3over 1α, 25-dihydroxyvitamin D3: Metabolism and molecular docking studies using rat CYP24A1

Published:2013-08-16 Issue:10 Volume:114 Page:2293-2305
ISSN:0730-2312
Container-title:Journal of Cellular Biochemistry
language:en
Short-container-title:J. Cell. Biochem.

Author:

Rhieu Steve Y.,Annalora Andrew J.¹,Wang Guochun,Flarakos Caroline C.²,Gathungu Rose M.²,Vouros Paul²,Sigüeiro Rita³,Mouriño Antonio³,Schuster Inge⁴,Palmore G. Tayhas R.,Reddy G. Satyanarayana⁵

Affiliation:

1. Department of Molecular Biology; The Scripps Research Institute; La Jolla; California; 92037

2. Department of Chemistry and Chemical Biology; Northeastern University; Boston; Massachusetts; 02115

3. Departamento de Química Orgánica, Laboratorio de Investigación Ignacio Ribas; Universidad de Santiago de Compostela; E-15706; Santiago de Compostela; Spain

4. Institute for Theoretical Chemistry; University of Vienna; Vienna; Austria

5. Epimer LLC; North Smithfield; Rhode Island; 02896

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jcb.24576/fullpdf

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3. The crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism;Annalora;J Mol Biol,2010

4. 1α, 25-dihdyroxy-3-epi-vitamin D3, a physiological metabolite of 1α,25-dihydroxyvitamin D3: Its production and metabolism in primary human keratinocytes;Astecker;Mol Cell Endocrinol,2000

5. Human 25-hydroxyvitamin D3-24-hydroxylase, a multicatalytic enzyme;Beckman;Biochemistry,1996

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