Oral administration of soluble β-glucans extracted fromGrifola frondosainduces systemic antitumor immune response and decreases immunosuppression in tumor-bearing mice

Author:

Masuda Yuki1,Inoue Hiroko1,Ohta Hiroya2,Miyake Ayumi2,Konishi Morichika,Nanba Hiroaki1

Affiliation:

1. Department of Microbial Chemistry; Kobe Pharmaceutical University; 4-19-1, Motoyama-kitamachi, Higashinada-ku; Kobe; 658-8558; Japan

2. Department of Genetic Biochemistry; Kyoto University Graduate School of Pharmaceutical Sciences, Sakyo; Kyoto; 606-8501; Japan

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference48 articles.

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2. Enhanced efficacy of therapeutic cancer vaccines produced by co-treatment with Mycobacterium tuberculosis heparin-binding hemagglutinin, a novel TLR4 agonist;Jung;Cancer Res,2011

3. Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk.) Sing. (an edible mushroom);Chihara;Cancer Res,1970

4. Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells;Lu;Clin Cancer Res,2011

5. beta-Glucans and dectin-1;Tsoni;Ann N Y Acad Sci,2008

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