Exploitation of cold-active cephalosporin C acylase by computer-aided directed evolution and its potential application in low-temperature biosynthesis of 7-aminocephalosporanic acid

Author:

Tang Cun-Duo12ORCID,Shi Hong-Ling1,Jiao Zhu-Jin1,Shi Hong-Fei1,Yao Lun-Guang1,Xu Jian-He2,Kan Yun-Chao1

Affiliation:

1. School of agricultural engineering, Henan Provincial Engineering Laboratory of Insect Bio-Reactor and Henan Key Laboratory of Ecological Security for Water Source Region of Mid-line of South-to-North; Nanyang Normal University; Nanyang China

2. School of biotechnology, State Key Laboratory of Bioreactor Engineering; East China University of Science and Technology; Shanghai China

Funder

The Scientific and Technological Project of Henan Province

The Scientific research and service platform fund of Henan Province

Water Source Region of Mid-line of South-to-North Diversion Project of Henan Province

The High School Key Research Project of Henan Province

The Special Funded Projects of Nanyang Normal University

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Pollution,Waste Management and Disposal,Fuel Technology,Renewable Energy, Sustainability and the Environment,General Chemical Engineering,Biotechnology

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