The Interplay between a Multifunctional Dehydratase Domain and a C-Methyltransferase Effects Olefin Shift in Ambruticin Biosynthesis-Reference-Cited by-同舟云学术

The Interplay between a Multifunctional Dehydratase Domain and a C-Methyltransferase Effects Olefin Shift in Ambruticin Biosynthesis

Published:2016-09-27 Issue:43 Volume:55 Page:13589-13592
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Berkhan Gesche¹²,Merten Christian³,Holec Claudia⁴,Hahn Frank¹²^ORCID

Affiliation:

1. Professur für Organische Chemie (Lebensmittelchemie), Fakultät für Biologie, Chemie und Geowissenschaften; Universität Bayreuth; Universitätsstrasse 30 95447 Bayreuth Germany

2. Zentrum für Biomolekulare Wirkstoffe; Leibniz Universität Hannover; Schneiderberg 38 30167 Hannover Germany

3. Ruhr Universität Bochum; Organische Chemie 2; Universitätsstrasse 150 44801 Bochum Germany

4. Institut für Bioorganische Chemie; Heinrich-Heine-Universität Düsseldorf im Forschungszentrum Jülich; Stetternicher Forst, Geb. 15.8 52426 Jülich Germany

Publisher

Wiley

Subject

General Chemistry,Catalysis

Reference28 articles.

1. The Biosynthetic Logic of Polyketide Diversity

2. Die biosynthetische Grundlage der Polyketid‐Vielfalt

3. Opportunities for enzyme catalysis in natural product chemistry

4. A Dehydratase Domain in Ambruticin Biosynthesis Displays Additional Activity as a Pyran-Forming Cyclase

5. Eine Dehydratase-Domäne in der Ambruticin-Biosynthese zeigt zusätzliche Aktivität als Pyran-bildende Cyclase

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