Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA-Reference-Cited by-同舟云学术

Non-Viral CRISPR/Cas Gene Editing In Vitro and In Vivo Enabled by Synthetic Nanoparticle Co-Delivery of Cas9 mRNA and sgRNA

Published:2016-12-16 Issue:4 Volume:56 Page:1059-1063
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Miller Jason B.¹^ORCID,Zhang Shuyuan²,Kos Petra¹,Xiong Hu¹,Zhou Kejin¹,Perelman Sofya S.³,Zhu Hao²,Siegwart Daniel J.¹^ORCID

Affiliation:

1. University of Texas Southwestern Medical Center; Simmons Comprehensive Cancer Center; Department of Biochemistry; Dallas TX 75390 USA

2. University of Texas Southwestern Medical Center; Children's Research Institute; Departments of Pediatrics and Internal Medicine; Dallas TX 75390 USA

3. University of Texas Southwestern Medical Center; Department of Microbiology; Dallas TX 75390 USA

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201610209/fullpdf

Reference53 articles.

1. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

2. Multiplex Genome Engineering Using CRISPR/Cas Systems

3. RNA-Guided Human Genome Engineering via Cas9

4. Applications of the CRISPR–Cas9 system in cancer biology

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