Antivitamin B12Inhibition of the Human B12-Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate-Reference-Cited by-同舟云学术

Antivitamin B12Inhibition of the Human B12-Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate

Published:2017-05-23 Issue:26 Volume:56 Page:7387-7392
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Ruetz Markus¹²,Shanmuganathan Aranganathan³,Gherasim Carmen²⁴,Karasik Agnes³,Salchner Robert¹⁵,Kieninger Christoph¹,Wurst Klaus⁶^ORCID,Banerjee Ruma²,Koutmos Markos³^ORCID,Kräutler Bernhard¹^ORCID

Affiliation:

1. Institute of Organic Chemistry and Center for Molecular Biosciences; University of Innsbruck; 6020 Innsbruck Austria

2. University of Michigan Medical School; Ann Arbor USA

3. Department of Biochemistry; Uniformed Services University of the Health Sciences; Bethesda USA

4. Current address: Department of Pathology; University of Utah School of Medicine; Salt Lake City UT USA

5. Current address: Watercryst GmbH & Co; Kematen Austria

6. Institute of General, Inorganic and Theoretical Chemistry; University of Innsbruck; Austria

Funder

Austrian Science Fund

National Institutes of Health

American Heart Association

Publisher

Wiley

Subject

General Chemistry,Catalysis

Reference45 articles.

1. Update on Cobalamin, Folate, and Homocysteine

2. The Many Faces of Vitamin B12: Catalysis by Cobalamin-Dependent Enzymes

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