Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7-Reference-Cited by-同舟云学术

Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7

Published:2017-11-07 Issue:49 Volume:56 Page:15555-15559
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Gerken Philip A.¹,Wolstenhulme Jamie R.¹,Tumber Anthony²,Hatch Stephanie B.²,Zhang Yijia¹,Müller Susanne²,Chandler Shane A.¹,Mair Barbara²,Li Fengling³,Nijman Sebastian M. B.²,Konietzny Rebecca²,Szommer Tamas²,Yapp Clarence²,Fedorov Oleg²,Benesch Justin L. P.¹^ORCID,Vedadi Masoud³,Kessler Benedikt M.²,Kawamura Akane¹^ORCID,Brennan Paul E.²^ORCID,Smith Martin D.¹^ORCID

Affiliation:

1. Chemistry Research Laboratory; University of Oxford; 12 Mansfield Road Oxford OX1 3TA UK

2. Structural Genomics Consortium and Target Discovery Institute; Nuffield Department of Medicine; University of Oxford; Roosevelt Drive Oxford OX3 7DQ UK

3. Structural Genomics Consortium; University of Toronto; Toronto Ontario M5G 1L7 Canada

Funder

Engineering and Physical Sciences Research Council

European Research Council

Biotechnology and Biological Sciences Research Council

Wellcome Trust

Innovative Medicines Initiative

National Institute of General Medical Sciences

Royal Society

Cancer Research UK

Publisher

Wiley