Efficient Uptake of 177 Lu-Porphyrin-PEG Nanocomplexes by Tumor Mitochondria for Multimodal-Imaging-Guided Combination Therapy

Author:

Yu Bo123,Wei Hao4,He Qianjun1,Ferreira Carolina A.2,Kutyreff Christopher J.2,Ni Dalong2ORCID,Rosenkrans Zachary T.5,Cheng Liang6,Yu Faquan3,Engle Jonathan W.2,Lan Xiaoli4,Cai Weibo257ORCID

Affiliation:

1. National-Regional Key Technology Engineering Laboratory for Medical Ultrasound; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging; School of Biomedical Engineering, Health Science Center; Shenzhen University; Shenzhen 518060 China

2. Departments of Radiology and Medical Physics; University of Wisconsin; Madison WI 53705 USA

3. Key Laboratory for Green Chemical Process of Ministry of Education; School of Chemical Engineering and Pharmacy; Wuhan Institute of Technology; Wuhan 430205 China

4. Department of Nuclear Medicine, Union Hospital, Tongji Medical College; Huazhong University of Science and Technology; Wuhan 430073 China

5. School of Pharmacy; University of Wisconsin; Madison WI 53705 USA

6. Institute of Functional Nano & Soft Materials (FUNSOM); Collaborative Innovation Center of Suzhou Nano Science and Technology; Soochow University; Suzhou 215123 China

7. University of Wisconsin Carbone Cancer Center; Madison WI 53705 USA

Funder

Foundation for the National Institutes of Health

the American Cancer Society

the National Natural Science Foundation of China

Shenzhen Peacock Plan

Postdoctoral Science Foundation of China

Publisher

Wiley

Subject

General Chemistry,Catalysis

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