Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain-Reference-Cited by-同舟云学术

Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain

Published:2013-10-31 Issue:46 Volume:52 Page:12081-12085
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Baggelaar Marc P.,Janssen Freek J.,van Esbroeck Annelot C. M.,den Dulk Hans,Allarà Marco,Hoogendoorn Sascha,McGuire Ross,Florea Bogdan I.,Meeuwenoord Nico,van den Elst Hans,van der Marel Gijsbert A.,Brouwer Jaap,Di Marzo Vincenzo,Overkleeft Herman S.,van der Stelt Mario

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201306295/fullpdf

Reference39 articles.

1. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

2. The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling

3. Multiple Functions of Endocannabinoid Signaling in the Brain

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