Molecular Dynamics Reveal that isoDGR-Containing Cyclopeptides Are True αvβ3 Antagonists Unable To Promote Integrin Allostery and Activation-Reference-Cited by-同舟云学术

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Molecular Dynamics Reveal that isoDGR-Containing Cyclopeptides Are True αvβ3 Antagonists Unable To Promote Integrin Allostery and Activation

Published:2012-06-20 Issue:31 Volume:51 Page:7702-7705
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Ghitti Michela,Spitaleri Andrea,Valentinis Barbara,Mari Silvia,Asperti Claudia,Traversari Catia,Rizzardi Gian Paolo,Musco Giovanna

Publisher

Wiley

Subject

General Chemistry,Catalysis

Reference28 articles.

1. Integrins in cancer: biological implications and therapeutic opportunities

2. The role of β3-integrins in tumor angiogenesis: context is everything

3. Integrins as therapeutic targets: lessons and opportunities

4. Linking integrin conformation to function

5. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics

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2. Comparative study of interaction energies between αIIbβ3 integrin and the peptidic, peptidomimetic and non-peptidic ligands by quantum mechanics FMO-PIEDA calculations;Chemical Papers;2023-06-10

3. The challenges and opportunities of αvβ3-based therapeutics in cancer: From bench to clinical trials;Pharmacological Research;2023-03

4. Molecular Modeling Insights into the Structure and Behavior of Integrins: A Review;Cells;2023-01-14

5. Targeting integrin pathways: mechanisms and advances in therapy;Signal Transduction and Targeted Therapy;2023-01-02

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