Pharmacophore Nanoarrays on DNA Origami Substrates as a Single-Molecule Assay for Fragment-Based Drug Discovery-Reference-Cited by-同舟云学术

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Pharmacophore Nanoarrays on DNA Origami Substrates as a Single-Molecule Assay for Fragment-Based Drug Discovery

Published:2018-10-09 Issue:45 Volume:57 Page:14873-14877
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Kielar Charlotte¹,Reddavide Francesco V.²³,Tubbenhauer Stefan¹,Cui Meiying²,Xu Xiaodan¹,Grundmeier Guido¹,Zhang Yixin²,Keller Adrian¹^ORCID

Affiliation:

1. Technical and Macromolecular Chemistry; Paderborn University; Warburger Str. 100 33098 Paderborn Germany

2. B CUBE-Center for Molecular Bioengineering; Technische Universität Dresden; Arnoldstr. 18 01307 Dresden Germany

3. DyNAbind GmbH; Arnoldstr. 20 01307 Dresden Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201806778/fullpdf

Reference41 articles.

1. DNA-Encoded Chemical Libraries: Advancing beyond Conventional Small-Molecule Libraries

2. Small-molecule discovery from DNA-encoded chemical libraries

3. PNA-encoded chemical libraries

4. Novel PTP1B inhibitors identified by DNA display of fragment pairs

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