General and Facile Route to Isomerically Pure Tricyclic Peptides Based on Templated Tandem CLIPS/CuAAC Cyclizations
Author:
Affiliation:
1. Bioinspired Organic Synthesis; Van't Hoff Institute for Molecular Sciences (HIMS); Science Park 904 1098 XH Amsterdam The Netherlands
2. Pepscan Therapeutics; Zuidersluisweg 2 8243 RC Lelystad The Netherlands
Funder
Stichting voor de Technische Wetenschappen
Publisher
Wiley
Subject
General Chemistry,Catalysis
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201709127/fullpdf
Reference35 articles.
1. Constrained Peptides with Target-Adapted Cross-Links as Inhibitors of a Pathogenic Protein-Protein Interaction
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3. Contemporary strategies for peptide macrocyclization
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5. The Future of Peptide-based Drugs
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