Pyrrole-Imidazole Polyamides Distinguish Between Double-Helical DNA and RNA
Author:
Publisher
Wiley
Subject
General Chemistry,Catalysis
Reference47 articles.
1. Design of peptides that bind in the minor groove of DNA at 5'-(A,T)G(A,T)C(A,T)-3' sequences by a dimeric side-by-side motif
2. Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin.
3. Binding affinities of synthetic peptides, pyridine-2-carboxamidonetropsin and 1-methylimidazole-2-carboxamidonetropsin, that form 2:1 complexes in the minor groove of double-helical DNA
4. Recognition of DNA by designed ligands at subnanomolar concentrations
5. Disruption of IRS-2 causes type 2 diabetes in mice
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