Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-Assisted Folding-Reference-Cited by-同舟云学术

Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-Assisted Folding

Published:2011-05-31 Issue:29 Volume:50 Page:6527-6529
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

de Araujo Aline Dantas,Callaghan Brid,Nevin Simon T.,Daly Norelle L.,Craik David J.,Moretta Melissa,Hopping Gene,Christie Macdonald J.,Adams David J.,Alewood Paul F.

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201101642/fullpdf

Reference31 articles.

1. Voltage-gated sodium channels and pain pathways

2. Voltage-Gated Sodium Channels and Hyperalgesia

3. Blockers of Voltage-Gated Sodium Channels for the Treatment of Central Nervous System Diseases

4. O-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits

5. Synthetic μO-Conotoxin MrVIB Blocks TTX-Resistant Sodium Channel NaV1.8 and Has a Long-Lasting Analgesic Activity

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