19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase-Reference-Cited by-同舟云学术

19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase

Published:2017-03-02 Issue:14 Volume:56 Page:3862-3866
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Abboud Martine I.¹,Hinchliffe Philip²,Brem Jürgen¹,Macsics Robert¹,Pfeffer Inga¹,Makena Anne¹,Umland Klaus-Daniel¹,Rydzik Anna M.¹,Li Guo-Bo¹,Spencer James²,Claridge Timothy D. W.¹,Schofield Christopher J.¹^ORCID

Affiliation:

1. Department of Chemistry; University of Oxford; 12 Mansfield Road OX1 3TA Oxford UK

2. School of Cellular and Molecular Medicine; University of Bristol; Bristol UK

Funder

Biochemical Society (GB)

Medical Research Council

Rhodes Scholarships

Wellcome Trust

SWON alliance

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/anie.201612185/fullpdf

Reference46 articles.

1. Metallo-β-lactamases: a last frontier for β-lactams?

2. Metallo-β-lactamases: Novel Weaponry for Antibiotic Resistance in Bacteria

3. Avibactam is a covalent, reversible, non- -lactam -lactamase inhibitor

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