A Red-Light-Activated Ruthenium-Caged NAMPT Inhibitor Remains Phototoxic in Hypoxic Cancer Cells-Reference-Cited by-同舟云学术

A Red-Light-Activated Ruthenium-Caged NAMPT Inhibitor Remains Phototoxic in Hypoxic Cancer Cells

Published:2017-08-09 Issue:38 Volume:56 Page:11549-11553
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Lameijer Lucien N.¹^ORCID,Ernst Daniël¹,Hopkins Samantha L.¹^ORCID,Meijer Michael S.¹,Askes Sven H. C.¹^ORCID,Le Dévédec Sylvia E.²^ORCID,Bonnet Sylvestre¹^ORCID

Affiliation:

1. Leiden Institute of Chemistry; Leiden University; Gorlaeus Laboratories; P.O Box 9502 2300 RA Leiden The Netherlands

2. Leiden Academic Centre for Drug Research; Leiden University; Gorlaeus Laboratories; P.O Box 9502 2300 RA Leiden The Netherlands

Funder

H2020 European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Wiley

Subject

General Chemistry,Catalysis

Reference56 articles.

1. An NAD+-dependent transcriptional program governs self-renewal and radiation resistance in glioblastoma

2. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents

3. Targeting Metabolic Scavenging in Pancreatic Cancer

4. Pharmacological Inhibition of Nicotinamide Phosphoribosyltransferase (NAMPT), an Enzyme Essential for NAD+ Biosynthesis, in Human Cancer Cells

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