Role of glycosylation on the ensemble of conformations in the MUC1 immunodominant epitope-Reference-Cited by-同舟云学术

Role of glycosylation on the ensemble of conformations in the MUC1 immunodominant epitope

Published:2019-11-14 Issue:1 Volume:26 Page:
ISSN:1075-2617
Container-title:Journal of Peptide Science
language:en
Short-container-title:J Pep Sci

Author:

Singh Jaideep¹,Her Cheenou¹,Supekar Nitin²³,Boons Geert‐Jan²³⁴,Krishnan Viswanathan V.¹⁵^ORCID,Brooks Cory L.¹^ORCID

Affiliation:

1. Department of ChemistryCalifornia State University 2555 E San Ramon Avenue Fresno CA 93740 USA

2. Department of ChemistryThe University of Georgia 140 Cedar Street Athens GA 30602 USA

3. Complex Carbohydrate Research CenterThe University of Georgia 315 Riverbend Road Athens GA 3062 USA

4. Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular ResearchUtrecht University Universiteitsweg 99 3584 CG Utrecht The Netherlands

5. Department of Pathology & Laboratory MedicineUniversity of California Davis School of Medicine 95616 Davis CA

Publisher

Wiley

Subject

Organic Chemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry,Structural Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psc.3229

Reference49 articles.

1. MUC1: a multifaceted oncoprotein with a key role in cancer progression

2. Intra- and Extra-Cellular Events Related to Altered Glycosylation of MUC1 Promote Chronic Inflammation, Tumor Progression, Invasion, and Metastasis

3. The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

4. Phase I trial of a murine antibody to MUC1 in patients with metastatic cancer: evidence for the activation of humoral and cellular antitumor immunity

5. A phase I study of PankoMab-GEX, a humanised glyco-optimised monoclonal antibody to a novel tumour-specific MUC1 glycopeptide epitope in patients with advanced carcinomas

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3. NMR of glycoproteins: profiling, structure, conformation and interactions;Current Opinion in Structural Biology;2021-06