Phase I trial of the mTOR inhibitor everolimus in combination with multi-agent chemotherapy in relapsed childhood acute lymphoblastic leukemia

Author:

Place Andrew E.1ORCID,Pikman Yana1,Stevenson Kristen E.2,Harris Marian H.3,Pauly Melinda4,Sulis Maria-Luisa5ORCID,Hijiya Nobuko6ORCID,Gore Lia7,Cooper Todd M.8,Loh Mignon L.9,Roti Giovanni10,Neuberg Donna S.2ORCID,Hunt Sarah K.1,Orloff-Parry Sarah1,Stegmaier Kimberly1,Sallan Stephen E.1,Silverman Lewis B.1

Affiliation:

1. Department of Pediatric Oncology; Dana-Farber Cancer Institute and Boston Children's Hospital; Boston Massachusetts

2. Department of Biostatistics and Computational Biology; Dana-Farber Cancer Institute; Boston Massachusetts

3. Department of Pathology; Boston Children's Hospital; Boston Massachusetts

4. Department of Pediatrics; Children's Healthcare of Atlanta/Emory University School of Medicine; Atlanta Georgia

5. Division of Pediatric Hematology; Oncology, and Stem Cell Transplant; Columbia University; New York City New York

6. Division of Hematology; Oncology, and Stem Cell Transplantation; Ann & Robert H. Lurie Children's Hospital/Northwestern University Feinberg School of Medicine; Chicago Illinois

7. Section of Hematology; Oncology, and Bone Marrow Transplantation; University of Colorado School of Medicine and Children's Hospital Colorado; Aurora Colorado

8. Cancer and Blood Disorders Center; Seattle Children's Hospital; Seattle Washington

9. Department of Pediatrics; Benioff Children's Hospital; University of California at San Francisco; San Francisco California

10. Department of Medicine and Surgery; University of Parma; Parma Italy

Funder

Division of Hematology/Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center

Alex's Lemonade Stand Foundation for Childhood Cancer

Dana-Farber Cancer Institute

Novartis Pharmaceuticals Corporation

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology, and Child Health

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