Repurposing hyperpolarization‐activated cyclic nucleotide‐gated channels as a novel therapy for breast cancer

Author:

Mok Ka‐Chun1,Tsoi Ho1,Man Ellen PS1,Leung Man‐Hong1,Chau Ka Man1,Wong Lai‐San2,Chan Wing‐Lok3,Chan Sum‐Yin2,Luk Mai‐Yee2,Chan Jessie Y.W.4,Leung Jackie K.M.4,Chan Yolanda H.Y.5,Batalha Sellma1,Lau Virginia6,Siu David C.W.6,Lee Terence K.W.7,Gong Chun1,Khoo Ui‐Soon1ORCID

Affiliation:

1. Department of Pathology Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong Hong Kong

2. Department of Clinical Oncology Queen Mary Hospital Hong Kong Hong Kong

3. Department of Clinical Oncology Li Ka Shing Faculty of Medicine The University of Hong Kong Hong Kong Hong Kong

4. Department of Surgery Pamela Youde Nethersole Eastern Hospital Hong Kong Hong Kong

5. Department of Surgery Kwong Wah Hospital Hong Kong Hong Kong

6. Department of Medicine The University of Hong Kong Hong Kong Hong Kong

7. Department of Applied Biology & Chemical Technology The Hong Kong Polytechnic University Hong Kong Hong Kong

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

Reference52 articles.

1. Hyperpolarization-Activated Cation Channels: From Genes to Function

2. Presynaptic facilitation by hyperpolarization-activated pacemaker channels

3. Exploring HCN channels as novel drug targets

4. High selectivity of the i(f) channel to Na+ and K+ in rabbit isolated sinoatrial node cells;Ho WK;Pflugers Arch,1994

5. Heart rate reduction via selective 'funny' channel blockers;Bucchi A;Curr Opin Pharmacol,2007

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