Insulin-like growth factor-1 receptor (IGF-1R) inhibition promotes expansion of human NK cells which maintain their potent antitumor activity against Ewing sarcoma cells-Reference-Cited by-同舟云学术

Insulin-like growth factor-1 receptor (IGF-1R) inhibition promotes expansion of human NK cells which maintain their potent antitumor activity against Ewing sarcoma cells

Published:2015-07-01 Issue:11 Volume:62 Page:1979-1985
ISSN:1545-5009
Container-title:Pediatric Blood & Cancer
language:en
Short-container-title:Pediatr Blood Cancer

Author:

Jamitzky Silke¹,Krueger Andrea-Caroline¹,Janneschuetz Saskia¹,Piepke Stephanie,Kailayangiri Sareetha¹,Spurny Christian¹,Rossig Claudia¹²,Altvater Bianca¹

Affiliation:

1. Department of Pediatric Hematology and Oncology; University Childreńs Hospital Muenster; Muenster Germany

2. Cells-in-Motion Cluster of Excellence (EXC 1003-CiM); University of Muenster; Muenster Germany

Funder

University of Muenster Medical School “Innovative Medical Research” (IMF) program

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/pbc.25619/fullpdf

Reference25 articles.

1. Ewing sarcoma: Biology-based therapeutic perspectives;Potratz;Pediatr Hematol Oncol,2012

2. Primary disseminated multifocal Ewing sarcoma: Results of the Euro-EWING 99 trial;Ladenstein;J Clin Oncol,2010

3. Cytotoxicity of activated natural killer cells against pediatric solid tumors;Cho;Clin Cancer Res,2010

4. NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways;Verhoeven;Mol Immunol,2008

5. Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: A possible therapeutic target;Scotlandi;Cancer Res,1996

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