Synthetic Analogues of Betulinic Acid as Potent Inhibitors of PS1/BACE1 Interaction to Reduce Aβ Generation-Reference-Cited by-同舟云学术

Synthetic Analogues of Betulinic Acid as Potent Inhibitors of PS1/BACE1 Interaction to Reduce Aβ Generation

Published:2016-12-20 Issue:1 Volume:35 Page:103-112
ISSN:1001-604X
Container-title:Chinese Journal of Chemistry
language:en
Short-container-title:Chin. J. Chem.

Author:

Zhang Chenlu¹,Wang Xiaoyin¹,Cui Jin²,Li Xiaohang²,Zhang Yangming¹,Wang Xin²,Gu Haifeng¹,Li Wei²,Xie Xin¹,Zhao Jian²,Pei Gang²³,Nan Fajun¹

Affiliation:

1. National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica; Chinese Academy of Sciences; Shanghai 201203 China

2. State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences; Chinese Academy of Sciences; Shanghai 200031 China

3. Translational Medical Center for Stem Cell Therapy, Shanghai East Hospital, School of Medicine; Tongji University; Shanghai 200092 China

Funder

the National Natural Science Foundation of China

Publisher

Wiley

Subject

General Chemistry

Reference19 articles.

1. A Century of Alzheimer's Disease

2. Alzheimer Mechanisms and Therapeutic Strategies

3. Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease

4. Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process

5. BACE1 (β-secretase) inhibitors for the treatment of Alzheimer's disease

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