Driven metal organic frameworks based hydrogels as wound dressing for anti‐inflammatory and antibacterial

Author:

Yang Li1ORCID,Li Jingqi2ORCID,Yang Liu3ORCID,Wang Wenxin1ORCID,Yue Zhengya1ORCID,Li Jialun1ORCID,Shi Lianxu1ORCID,Sun Tiedong1ORCID

Affiliation:

1. College of Chemistry, Chemical Engineering and Resource Utilization Northeast Forestry University Harbin China

2. State Key Laboratory of Medicinal Chemical Biology, Research Center for Analytical Sciences, Tianjin Key Laboratory of Molecular Recognition and Biosensing, and Institute of Polymer Chemistry, College of Chemistry Nankai University Tianjin China

3. Wuxi School of Medicine Jiangnan University Wuxi China

Abstract

Metal organic frameworks (MOFs) are porous crystalline materials composed of metal ions and organic ligands by coordinate bonds. They have adjustable porous structure and ordered structure. As a porous, soft, and extracellular matrix‐like polymer, hydrogel is a strong competitor for wound dressings and has attracted much attention in recent years. MOF‐based hydrogels (MOF–hydrogels), as a new type of intelligent wound dressing, breaks the limitations of traditional gauze dressing, expands the application range of dressing, and updates the definition of dressing. The combination of MOF and hydrogel transcends the function of single component and combines the advantages of MOF and hydrogel. In this paper, the application of MOF–hydrogels as wound dressing will be systematically and comprehensively described from the working principles of MOF–hydrogels for anti‐inflammatory and antibacterial. And the prospect of its development trend in the future is made, which provides a new idea for its future development direction.

Funder

Natural Science Foundation of Heilongjiang Province

National Natural Science Foundation of China

Publisher

Wiley

Subject

Inorganic Chemistry,General Chemistry

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