Injectable Hydrogels: A Paradigm Tailored with Design, Characterization, and Multifaceted Approaches

Author:

Singhal Rishika1,Sarangi Manoj Kumar1ORCID,Rath Goutam2

Affiliation:

1. Department of Pharmaceutics Amity Institute of Pharmacy Amity University Malhaur Railway Station Road, Gomti Nagar Lucknow Uttar Pradesh 201313 India

2. Department of Pharmaceutics School of Pharmaceutical Sciences Siksha ‘O’ Anusandhan University Bhubaneswar Odisha 751030 India

Abstract

AbstractBiomaterials denoting self‐healing and versatile structural integrity are highly curious in the biomedicine segment. The injectable and/or printable 3D printing technology is explored in a few decades back, which can alter their dimensions temporarily under shear stress, showing potential healing/recovery tendency with patient‐specific intervention toward the development of personalized medicine. Thus, self‐healing injectable hydrogels (IHs) are stunning toward developing a paradigm for tissue regeneration. This review comprises the designing of IHs, rheological characterization and stability, several benchmark consequences for self‐healing IHs, their translation into tissue regeneration of specific types, applications of IHs in biomedical such as anticancer and immunomodulation, wound healing and tissue/bone regeneration, antimicrobial potentials, drugs, gene and vaccine delivery, ocular delivery, 3D printing, cosmeceuticals, and photothermal therapy as well as in other allied avenues like agriculture, aerospace, electronic/electrical industries, coating approaches, patents associated with therapeutic/nontherapeutic avenues, and numerous futuristic challenges and solutions.

Publisher

Wiley

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