Portable in situ temperature‐dependent spectroscopy on a low‐cost microfluidic platform integrated with a battery‐powered thermofoil heater

Author:

Katla Sai Krishna1,Zhou Wan1,Tavakoli Hamed1,Méndez Elvia Lilia Padilla1,Li Xiujun123ORCID

Affiliation:

1. Department of Chemistry and Biochemistry University of Texas at El Paso El Paso Texas USA

2. Border Biomedical Research Center, & Forensic Science University of Texas at El Paso El Paso Texas USA

3. Environmental Science and Engineering University of Texas at El Paso El Paso Texas USA

Abstract

AbstractA low‐cost microfluidic platform integrated with a flexible heater was developed for in situ temperature‐dependent spectroscopic measurement at the point of care. After verifying the system by comparing on‐chip spectroscopic measurement of methylene blue with the conventional spectroscopy, we demonstrated its applications in temperature‐dependent absorption spectroscopy of a model biomolecule, curcumin. The system is portable, battery‐powered and requires ultra‐low volumes of analytes, which is highly suitable for point‐of‐care characterization.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

Biomedical Engineering,Biomaterials

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