Potential of a Cetuximab-based radioimmunotherapy combined with external irradiation manifests in a 3-D cell assay

Author:

Ingargiola M.12,Runge R.13,Heldt J.-M.14,Freudenberg R.13,Steinbach J.14,Cordes N.125,Baumann M.125,Kotzerke J.13,Brockhoff G.6,Kunz-Schughart L.A.12

Affiliation:

1. OncoRay-National Center for Radiation Research in Oncology; Medical Faculty Carl Gustav Carus; TU Dresden; Dresden Germany

2. Institute of Radiooncology, Helmholtz-Zentrum Dresden-Rossendorf (HZDR); Dresden Germany

3. Department of Nuclear Medicine; Medical Faculty and University Hospital Carl Gustav Carus, TU Dresden; Dresden Germany

4. Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR); Dresden Germany

5. Department of Radiation Oncology; Medical Faculty and University Hospital Carl Gustav Carus, TU Dresden; Dresden Germany

6. Department of Gynecology and Obstetrics; University of Regensburg; Regensburg Germany

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference59 articles.

1. Clinical radioimmunotherapy-the role of radiobiology;Pouget;Nat Rev Clin Oncol,2011

2. Cancer radioimmunotherapy;Sharkey;Immunotherapy,2011

3. Antibody-radionuclide conjugates for cancer therapy: historical considerations and new trends;Steiner;Clin Cancer Res,2011

4. Targeted therapy of cancer with radiolabeled antibodies;Goldenberg;J Nucl Med,2002

5. Targeted therapy of athymic mice bearing GW-39 human colonic cancer micrometastases with 131I-labeled monoclonal antibodies;Blumenthal;Cancer Res,1992

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