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Adaptive dose modification for phase I clinical trials

  • Published:2016-03-29 Issue:20 Volume:35 Page:3497-3508
  • ISSN:0277-6715
  • Container-title:Statistics in Medicine
  • language:en
  • Short-container-title:Statist. Med.

Author:

Chu Yiyi1,Pan Haitao2,Yuan Ying2

Affiliation:

1. Department of Biostatistics; The University of Texas School of Public Health; Houston 77030 TX U.S.A.

2. Department of Biostatistics; The University of Texas MD Anderson Cancer Center; Houston 77030 TX U.S.A.

Funder

National Science Foundation of China

China Postdoctoral Science Foundation funded project

Natura Science Basic Research Plan of Shaanxi Province of China

Scientific Research Project of Education Department of Shaanxi Province

Publisher

Wiley

Subject

Statistics and Probability,Epidemiology

Reference21 articles.

1. Design and analysis of phase I clinical trials;Storer;Biometrics,1989

2. Continual reassessment method: a practical design for phase 1 clinical trials in cancer;O'Quigley;Biometrics,1990

3. Statistical Decision Theory and Related Topics V;Durham,1994

4. Bayesian decision procedures for dose determining experiments;Whitehead;Statistics in medicine,1995

5. Isotonic designs for phase I trials;Leung;Controlled clinical trials,2001

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