Two novel fusion genes,AIF1L-ETV6andABL1-AIF1L, result together withETV6-ABL1from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin

Author:

Lukes Jr Julius12ORCID,Potuckova Eliska12,Sramkova Lucie123,Stary Jan23,Starkova Julia12ORCID,Trka Jan123,Votava Felix4,Zuna Jan123,Zaliova Marketa123ORCID

Affiliation:

1. CLIP - Childhood Leukaemia Investigation Prague; Prague Czech Republic

2. Department of Paediatric Haematology and Oncology; Second Faculty of Medicine, Charles University; Prague Czech Republic

3. University Hospital Motol; Prague Czech Republic

4. Department of Pediatrics; 3rd Faculty of Medicine, Charles University; Prague Czech Republic

Funder

Czech Health Research Council

Charles University

Ministry of Health of the Czech Republic

University Hospital Motol, Prague, Czech Republic

Ministry of Education, Youth and Sports

Publisher

Wiley

Subject

Cancer Research,Genetics

Reference22 articles.

1. Characterization of leukemias with ETV6-ABL1 fusion;Zaliova;Haematologica.,2016

2. Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia;Golub;Mol Cell Biol.,1996

3. p210BCR/ABL, p190BCR/ABL, and TEL/ABL activate similar signal transduction pathways in hematopoietic cell lines;Okuda;Oncogene.,1996

4. Haemopoietic transformation by the TEL/ABL oncogene;Hannemann;Br J Haematol.,1998

5. The leukaemic oncoproteins Bcr-Abl and Tel-Abl (ETV6/Abl) have altered substrate preferences and activate similar intracellular signalling pathways;Voss;Oncogene.,2000

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