Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure-Reference-Cited by-同舟云学术

Cytogenetic analysis of chimeric antibody-producing CHO cells in the course of dihydrofolate reductase-mediated gene amplification and their stability in the absence of selective pressure

Published:1999-09-20 Issue:6 Volume:64 Page:741-749
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol. Bioeng.

Author:

Kim Sang Jick,Lee Gyun Min

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference33 articles.

1. Telomeric and Nontelomeric (TTAGGG)n Sequences in Gene Amplification and Chromosome Stability

2. Structure and function of telomeres

3. 1989. Preferential loss of chromosomes containing amplified DNA regions in cultured cells. In: editors. Mechanism of chromosome distribution and aneuploidy. New York: Liss. p 271-276.

4. Expression of Fragile Sites Triggers Intrachromosomal Mammalian Gene Amplification and Sets Boundaries to Early Amplicons

5. Occurrence and evolution of homogeneously staining regions may be due to breakage-fusion-bridge cycles following telomere loss

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