Possible factor for nonlinear pharmacokinetics of TAK‐603, a new antirheumatic agent, in rats
Author:
Affiliation:
1. Drug Analysis and Pharmacokinetics Research Laboratories, Pharmaceutical Development Division, Takeda Chemical Industries Ltd., Osaka, Japan
2. Department of Hospital Pharmacy, Kobe University Hospital, Kobe, Japan
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/%28SICI%291099-081X%28199901%2920%3A1%3C11%3A%3AAID-BDD147%3E3.0.CO%3B2-%23
Reference19 articles.
1. Studies on Disease-Modifying Antirheumatic Drugs: Synthesis of Novel Quinoline and Quinazoline Derivatives and Their Anti-inflammatory Effect
2. Immunomodulating and articular protecting activities of a new anti-rheumatic drug, TAK-603
3. Disposition of a new antirheumatic agent, ethyl 4‐(3,4‐dimethoxyphenyl)‐6,7‐dimethoxy‐2‐(1,2,4‐triazol‐1‐yl‐methyl)quinoline‐3‐carboxylate (TAK‐603), in rats and dogs;Tagawa Y.;Arzneim‐Forsch./Drug Res.,1998
4. Y.Tagawa K.Miwa K.Yamashita S.Tanayama Y.YoshimuraandY.Tanigawara Product‐inhibition induced nonlinear pharmacokinetics of a new antirheumatic agent TAK‐603 in humans. Eighth North American International Society for the Study of Xenobiotics Hilton Head South Carolina October 26–30 1997(Abstract 246).
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1. Impact of P-Glycoprotein on Intestinal Absorption of an Inhibitor of Apoptosis Protein Antagonist in Rats: Mechanisms of Nonlinear Pharmacokinetics and Food Effects;Pharmaceutical Research;2018-08-13
2. Synthesis and Properties of Diarylamino-Substituted Linear and Dendritic Oligoquinolines for Organic Light-Emitting Diodes;Bulletin of the Korean Chemical Society;2012-05-20
3. Syntheses of metabolites of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (TAK-603);Tetrahedron;2006-09
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