Determination of cefoperazone and sulbactam in serum by HPLC-MS/MS: An adapted method for therapeutic drug monitoring in children

Author:

Wu Xiu-Jun1,Huang Xin2,Shi Hai-Yan23ORCID,Chen Xing-Kai3,Dong Qian3,Hao Guo-Xiang3,Li Yan2,Zheng Yi3,Zhao Wei23ORCID

Affiliation:

1. Laboratory of Clinical Pharmacokinetic of TCM; Affiliated Hospital of Liaoning University of Traditional Medicine; Shenyang China

2. Department of Pharmacy, Shandong Provincial Qianfoshan Hospital; Shandong University; Jinan China

3. Department of Clinical Pharmacy, School of Pharmaceutical Sciences; Shandong University; Jinan China

Funder

Young Scholars Program of Shandong University

Young Taishan Scholars Program

National Science and Technology Major Projects

Young Taishan Scholars Program and Young Scholars Program of Shandong University

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference20 articles.

1. Simultaneous determination of nine β-lactam antibiotics in human plasma by an ultrafast hydrophilic-interaction chromatography-tandem mass spectrometry;Abdulla;Journal of Chromatography B: Analytical Technology in Biomedicine and Life Sciences,2017

2. Development and validation of stability indicating HPLC methods for related substances and assay analyses of amoxicillin and potassium clavulanate mixtures;Bellur Atici;Journal of Pharmaceutical and Biomedical Analusis,2017

3. Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method;Carlier;International Journal of Antimicrobial Agents,2012

4. Cefoperazone pharmacokinetics meningitis;Chartrand;The Journal of Pediatrics,1983

5. Stability, compatibility and microbiological activity studies of meropenem-clavulanate potassium;Cielecka-Piontek;Journal of Antibiotics (Tokyo),2015

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