Antioxidant and antihyperlipidemic effects of hawthorn extract (Crataegus oxyacantha) in broiler chickens

Author:

Ahmadipour Behnam1ORCID,Kalantar Majid2,Abaszadeh Samira1,Hassanpour Hossein3

Affiliation:

1. Department of Animal Science Faculty of Agriculture Shahrekord University Shahrekord Iran

2. Department of Animal Science Qom's Agricultural Research and Education Center Agricultural Research, Education, and Extension Organization, Jihad‐e‐Keshavarzi Ministry Qom Iran

3. Department of Basic Sciences Faculty of Veterinary Medicine Shahrekord University Shahrekord Iran

Abstract

AbstractBackgroundOne of the main problems in the poultry industry is excess body fat, and the anti‐fat effect of Cratagus extract has been confirmed in several studies.ObjectivesThe present study was carried out to investigate the effects of hawthorn extract (Crataegus oxyacantha) on growth performance, haematological variables and hepatic gene expression in broiler chickens reared at high altitude (2100 m).MethodsA total of 225‐day‐old chicks (Ross 308) were randomly distributed into three treatments. Experimental treatments were prepared by adding 0.0, 0.2 and 0.4 mL of hawthorn extract per litre of consumption of water.ResultsThe results showed that weight gain and feed conversion ratio were significantly improved and abdominal fat decreased by consumption of two levels of Crateagus extract when compared to the control (< 0.05). Consumption of hawthorn extract decreased circulatory levels of malondialdehyde, triacylglycerol, total cholesterol and low‐density lipoproteins cholesterol but increased ferric reducing antioxidant power and high‐density lipoproteins cholesterol (p < 0.05). Hawthorn extract caused an up‐regulation of catalase, superoxide dismutase1, glutathione peroxidase1 and peroxisome proliferator‐activated receptor alpha but reduced the expression of key lipogenic enzymes (< 0.05).ConclusionsOverall, consumption of 0.4 mL hawthorn extract per litre of drinking water, improved growth performance, suppressed lipogenesis and enhanced antioxidant response.

Publisher

Wiley

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