In vitro and in vivo characterization of several functionalized ultrasmall particles of iron oxide, vectorized against amyloid plaques and potentially able to cross the blood-brain barrier: toward earlier diagnosis of Alzheimer's disease by molecular imag

Author:

Ansciaux Emilie1,Burtea Carmen1,Laurent Sophie1,Crombez Deborah1,Nonclercq Denis2,Vander Elst Luce1,Muller Robert N.13

Affiliation:

1. Department of General, Organic and Biomedical Chemistry, NMR and Molecular Imaging Laboratory; University of Mons; Avenue Maistriau 19, Mendeleev Building B-7000 Mons Belgium

2. Laboratory of Histology; University of Mons; Pentagon - 1B, 6 Avenue du Champ de Mars B-7000 Mons Belgium

3. Center for Microscopy and Molecular Imaging; 8, rue Adrienne Bolland 6041 Gosselies Belgium

Funder

Fonds National de la Recherche Scientifique

STICHTING VOOR ALZHEIMER ONDERZOEK – FONDATION POUR LA RECHERCHE SUR LA MALADIE D’ALZHEIMER

UMons-100 fellowship

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging

Reference54 articles.

1. Mild cognitive impairment or pre-demential Alzheimer's disease?;Sarazin;Rev Neurol (Paris),2002

2. Cerebral amyloid angiopathy - a disease or age-related condition;Soffer;Isr Med Assoc J,2006

3. Medicine - the amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics;Hardy;Science,2002

4. The role of tau in Alzheimer's disease and related disorders;Medeiros;CNS Neurosci Ther,2011

5. Oxidative stress, antioxidants and neurodegenerative diseases;Casetta;Curr Pharm Des,2005

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