Rearrangements of theMLLgene are influenced by DNA secondary structure, potentially mediated by topoisomerase II binding

Author:

Le Hongan,Singh Sheetal,Shih Shyh-Jen,Du Nga,Schnyder Sabine,Loredo Grace A.,Bien Christine,Michaelis Laura,Toor Amir,Diaz Manuel O.,Vaughan Andrew T.

Publisher

Wiley

Subject

Cancer Research,Genetics

Reference29 articles.

1. Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion;Alexander;Cancer Res,2001

2. MLL rearrangements emerge during spontaneous apoptosis of clinical blood samples;Basecke;Leukemia,2006

3. Apoptotic triggers initiate translocations within the MLL gene involving the nonhomologous end joining repair system;Betti;Cancer Res,2001

4. Apoptotic stimuli initiate MLL-AF9 translocations that are transcribed in cells capable of division;Betti;Cancer Res,2003

5. Cleavage of the MLL gene by activators of apoptosis is independent of topoisomerase II activity;Betti;Leukemia,2005

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