Tecovirimat therapy for severe monkeypox infection: Longitudinal assessment of viral titers and clinical response pattern—A first case‐series experience-Reference-Cited by-同舟云学术

Tecovirimat therapy for severe monkeypox infection: Longitudinal assessment of viral titers and clinical response pattern—A first case‐series experience

Published:2022-10-20 Issue:1 Volume:95 Page:
ISSN:0146-6615
Container-title:Journal of Medical Virology
language:en
Short-container-title:Journal of Medical Virology

Author:

Hermanussen Lennart¹^ORCID,Grewe Ilka¹,Tang Hui Ting²,Nörz Dominik²,Bal Lukas C.¹,Pfefferle Susanne²,Unger Stefan³,Hoffmann Christian⁴,Berzow Dirk⁵,Kohsar Matin¹⁶,Aepfelbacher Martin²,Lohse Ansgar W.¹⁷,Addo Marylyn M.¹⁷⁸,Lütgehetmann Marc²⁷,Schulze zur Wiesch Julian¹⁷,Schmiedel Stefan¹

Affiliation:

1. Department of Internal Medicine, Gastroenterology and Hepatology, Sections of Infectious Diseases and Tropical Medicine University Medical Center Hamburg‐Eppendorf Hamburg Germany

2. Institute of Medical Microbiology, Virology and Hygiene University Medical Center Hamburg‐Eppendorf (UKE) Hamburg Germany

3. Institute for interdisciplinary medicine (ifi) Hamburg Germany

4. ICH Hamburg‐Stendal Hamburg Germany

5. Praxis for Infectiology Hamburg Germany

6. Department of Tropical Medicine Berhard Nocht Institute for Tropical Medicine Hamburg Germany

7. German Center for Infection Research Hamburg‐Lubeck‐Borstel‐Riems Hamburg Germany

8. Institute for Infection research and Vaccine development (IIRVD) University Medical Center Hamburg‐Eppendorf (UKE) Hamburg Germany

Publisher

Wiley

Subject

Infectious Diseases,Virology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jmv.28181

Reference21 articles.

1. European Medicines Agency (EMA).Drug Information on Tecovirimat.https://www.ema.europa.eu/en/medicines/human/EPAR/tecovirimat-siga

2. The development and approval of tecoviromat (TPOXX®), the first antiviral against smallpox

3. An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

4. Effects of Treatment Delay on Efficacy of Tecovirimat Following Lethal Aerosol Monkeypox Virus Challenge in Cynomolgus Macaques

5. Oral Tecovirimat for the Treatment of Smallpox

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