Rapid identification of phase I and II metabolites of artemisinin antimalarials using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange technique

Author:

Liu Tian,Du Fuying,Wan Yakun,Zhu Fanping,Xing Jie

Publisher

Wiley

Subject

Spectroscopy

Reference16 articles.

1. Antimalarial drug resistance;White;J. Clin. Invest.,2004

2. Artemisinin resistance: current status and scenarios for containment;Dondorp;Nat. Rev. Microbiol.,2010

3. Possible modes of action of the artemisinin-type compounds;Olliaro;Trends Parasitol.,2001

4. Artemisinin pharmacokinetics is time-dependent during repeated oral administration in healthy male adults;Ashton;Drug Metab. Dispos.,1998

5. Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin;Svensson;Br. J. Clin. Pharmacol.,1999

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