18F-fluoromisonidazole uptake in advanced stage non-small cell lung cancer: A voxel-by-voxel PET kinetics study

Author:

McGowan Daniel R.12,Macpherson Ruth E.3,Hackett Sara L.1,Liu Dan1,Gleeson Fergus V.13,McKenna W. Gillies14,Higgins Geoff S.14,Fenwick John D.1

Affiliation:

1. Cancer Research UK/MRC Oxford Institute for Radiation Oncology; Gray Laboratories; Department of Oncology; University of Oxford; Oxford UK

2. Radiation Physics and Protection; Oxford University Hospitals NHS Foundation Trust; Oxford UK

3. Department of Radiology; Oxford University Hospitals NHS Foundation Trust; Oxford UK

4. Department of Oncology; Oxford University Hospitals NHS Foundation Trust; Oxford UK

Funder

National Institute for Health Research

Cancer Research UK

Cancer Research UK Clinician Scientist Award

Cancer Research UK Career Development Fellowship

Oxford ECMC

Oxford Cancer Imaging Centre

CRUK Oxford Centre

Novartis

Medical Research Council

Cancer Research UK/MRC Oxford Institute for Radiation Oncology

Publisher

Wiley

Subject

General Medicine

Reference36 articles.

1. Radiolabeled fluoromisonidazole as an imaging agent for tumor hypoxia;Rasey;Int J Radiat Oncol Biol Phys,1989

2. A modeling approach for quantifying tumor hypoxia with [F-18]fluoromisonidazole PET time-activity data;Casciari;Med Phys,1995

3. Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy;Eschmann;J Nucl Med,2005

4. Hypoxia imaging with [18F]HX4 PET in NSCLC patients: defining optimal imaging parameters;Zegers;Radiother Oncol,2013

5. PET imaging of tumor hypoxia using 18F-fluoroazomycin arabinoside in stage III-IV non-small cell lung cancer patients;Bollineni;J Nucl Med,2013

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