Proteomics profiling of colorectal cancer progression identifies PLOD2 as a potential therapeutic target

Author:

Shao Yingkuan123ORCID,Xu Kailun123ORCID,Zheng Xi123,Zhou Biting1,Zhang Xiuli4,Wang Lin5,Sun Yaoting23,Li Dan1,Chen Ting1,Wang Jian6,Yu Shaojun6,Sun Lifeng6,Xu Xiaoming7,Dai Shaozhi23,Gao Huanhuan23,Ruan Guan23,Liu Wei23,Cai Xue23,Zhu Tiansheng23,Qi Lina1,Chen Jiani1,Hu Wangxiong1,Weng Xingyue1,Zhu Yi23,Xiang Xueping7,Hu Zhiyuan489,Li Jinfan7,Chen Lirong7,Shao Jimin110ORCID,Zheng Shu1ORCID,Guo Tiannan23ORCID

Affiliation:

1. Key Laboratory of Cancer Prevention and Intervention Ministry of Education Department of Breast Surgery and Oncology Second Affiliated Hospital School of Medicine Cancer Institute Zhejiang University Hangzhou Zhejiang 310009 P. R. China

2. Zhejiang Provincial Laboratory of Life Sciences and Biomedicine Key Laboratory of Structural Biology of Zhejiang Province School of Life Sciences Westlake University 18 Shilongshan Road Hangzhou Zhejiang 310024 P. R. China

3. Institute of Basic Medical Sciences Westlake Institute for Advanced Study 18 Shilongshan Road Hangzhou Zhejiang 310024 P. R. China

4. CAS Key Laboratory of Standardization and Measurement for Nanotechnology CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China Beijing 100190 P. R. China

5. Zhejiang Provincial Key Laboratory of Pancreatic Disease The First Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang P. R. China

6. Department of Colorectal Surgery the Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang 310009 P. R. China

7. Department of Pathology The Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310009 P. R. China

8. School of Nanoscience and Technology Sino‐Danish College University of Chinese Academy of Sciences Beijing 100049 P. R. China

9. Fujian Provincial Key Laboratory of Brain Aging and Neurodegenerative Diseases School of Basic Medical Sciences Fujian Medical University Fuzhou Fujian 350108 P. R. China

10. Department of Pathology and Pathophysiology Key Laboratory of Disease Proteomics of Zhejiang Province Zhejiang University School of Medicine Hangzhou Zhejiang 310058 P. R. China

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cancer Research,Oncology

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