P300/CBP‐associated factor (PCAF)‐mediated acetylation of Fascin at lysine 471 inhibits its actin‐bundling activity and tumor metastasis in esophageal cancer

Author:

Cheng Yin‐Wei12,Zeng Fa‐Min1,Li Da‐Jia1,Wang Shao‐Hong3,He Jian‐Zhong14,Guo Zhen‐Chang15,Nie Ping‐Juan1,Wu Zhi‐Yong3,Shi Wen‐Qi1,Wen Bing1,Xu Xiu‐E14,Liao Lian‐Di14,Li Zhi‐Mao14,Wu Jian‐Yi1,Zhan Jun6,Zhang Hong‐Quan6,Chang Zhi‐Jie7,Zhang Kai5ORCID,Xu Li‐Yan124ORCID,Li En‐Min1ORCID

Affiliation:

1. The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area Department of Biochemistry and Molecular Biology Shantou University Medical College Shantou Guangdong 515041 P. R. China

2. Institute of Basic Medical Science Cancer Research Center Shantou University Medical College Shantou Guangdong 515041 P. R. China

3. Shantou Central Hospital Affiliated Shantou Hospital of Sun Yat‐sen University Shantou Guangdong 515041 P. R. China

4. Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology Institute of Oncologic Pathology Shantou University Medical College Shantou Guangdong 515041 P. R. China

5. Tianjin Key Laboratory of Medical Epigenetics Department of Biochemistry and Molecular Biology School of Basic Medical Sciences Tianjin Medical University Tianjin 300070 P. R. China

6. State Key Laboratory of Natural and Biomimetic Drugs Peking University Health Science Center Beijing 100191 P. R. China

7. School of Medicine Tsinghua University Beijing 100084 P. R. China

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Wiley

Subject

Cancer Research,Oncology

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