Design of synthetic promoters for controlled expression of therapeutic genes in retinal pigment epithelial cells
Author:
Affiliation:
1. Department of Chemical and Biological Engineering University of Sheffield Sheffield UK
2. Research and Early Development REGENXBIO Inc. Rockville Maryland USA
Funder
REGENXBIO
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27713
Reference48 articles.
1. Human Retinal Pigment Epithelium Cells as Functional Models for the RPE In Vivo
2. A New Strategy to Identify and Annotate Human RPE-Specific Gene Expression
3. Functional annotation of the human retinal pigment epithelium transcriptome
4. The Upstream Region of the Rpe65 Gene Confers Retinal Pigment Epithelium-specific Expression in Vivo and in Vitro and Contains Critical Octamer and E-box Binding Sites
5. In silico design of context-responsive mammalian promoters with user-defined functionality
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Accelerated maturation of ARPE‐19 cells for the translational assessment of gene therapy;The FASEB Journal;2024-09
2. Replenishing IRAK-M expression in retinal pigment epithelium attenuates outer retinal degeneration;Science Translational Medicine;2024-06-05
3. Subretinal AAV delivery of RNAi-therapeutics targeting VEGFA reduces choroidal neovascularization in a large animal model;Molecular Therapy - Methods & Clinical Development;2024-06
4. Molecular design of controllable recombinant adeno‐associated virus (AAV) expression systems for enhanced vector production;Biotechnology Journal;2024-06
5. Corneal Regeneration Using Gene Therapy Approaches;Cells;2023-04-28
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3