Model‐Based Prediction of Irinotecan‐Induced Grade 4 Neutropenia in Advanced Cancer Patients: Influence of Demographic and Clinical Factors-Reference-Cited by-同舟云学术

Model‐Based Prediction of Irinotecan‐Induced Grade 4 Neutropenia in Advanced Cancer Patients: Influence of Demographic and Clinical Factors

Published:2022-05-18 Issue:2 Volume:112 Page:316-326
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharma and Therapeutics

Author:

Karas Spinel¹,Mathijssen Ron H. J.²,van Schaik Ron H. N.³,Forrest Alan¹,Wiltshire Tim¹,Innocenti Federico⁴,Bies Robert R.⁵⁶

Affiliation:

1. Division of Pharmacotherapy and Experimental Therapeutics UNC Eshelman School of Pharmacy University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

2. Department of Medical Oncology Erasmus MC Cancer Institute Rotterdam The Netherlands

3. Department of Clinical Chemistry Erasmus MC Rotterdam The Netherlands

4. Oncology Early Development AbbVie, Inc. South San Francisco California USA

5. Department of Pharmaceutical Sciences University at Buffalo School of Pharmacy and Pharmaceutical Sciences State University of New York at Buffalo Buffalo New York USA

6. Institute for Computational and Data Sciences University at Buffalo State University of New York at Buffalo Buffalo New York USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpt.2621

Reference47 articles.

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2. Phase I and pharmacokinetic trial of weekly CPT-11.

3. Phase I clinical and pharmacokinetic study of irinotecan, fluorouracil, and leucovorin in patients with advanced solid tumors.

4. Phase III Comparison of Two Irinotecan Dosing Regimens in Second-Line Therapy of Metastatic Colorectal Cancer

5. Risk and Timing of Neutropenic Events in Adult Cancer Patients Receiving Chemotherapy: The Results of a Prospective Nationwide Study of Oncology Practice

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