Bayesian estimation in NONMEM

Author:

Johnston Curtis K.1,Waterhouse Timothy1ORCID,Wiens Matthew1ORCID,Mondick John1,French Jonathan1ORCID,Gillespie William R.1ORCID

Affiliation:

1. Metrum Research Group Tariffville Connecticut USA

Abstract

AbstractBayesian estimation is a powerful but underutilized tool for answering drug development questions. In this tutorial, the principles of Bayesian model development, assessment, and prior selection will be outlined. An example pharmacokinetic (PK) model will be used to demonstrate the implementation of Bayesian modeling using the nonlinear mixed‐effects modeling software NONMEM.

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Bayesian estimation in veterinary pharmacology: A conceptual and practical introduction;Journal of Veterinary Pharmacology and Therapeutics;2024-02-22

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