Role of pharmacometrics and systems pharmacology in facilitating efficient dose optimization in oncology-Reference-Cited by-同舟云学术

Role of pharmacometrics and systems pharmacology in facilitating efficient dose optimization in oncology

Published:2023-11 Issue:11 Volume:12 Page:1569-1572
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacom & Syst Pharma

Author:

Jayachandran Priya¹^ORCID,Desikan Rajat²^ORCID,Krishnaswami Sriram³,Hennig Stefanie⁴⁵^ORCID

Affiliation:

1. Regeneron Pharmaceuticals, Inc. Tarrytown New York USA

2. Clinical Pharmacology Modeling & Simulation GlaxoSmithKline (GSK) Stevenage Hertfordshire UK

3. Oncology Research and Development Pfizer Groton Connecticut USA

4. Certara, Inc. Melbourne Victoria Australia

5. School of Clinical Sciences, Faculty of Health Queensland University of Technology Brisbane Queensland Australia

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://ascpt.onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.13066

Reference21 articles.

1. Food and Drug Administration.Project Optimus: reforming the dose optimization and dose selection paradigm in oncology.2023.https://www.fda.gov/about‐fda/oncology‐center‐excellence/project‐optimus.

2. Model‐based prediction of effective target exposure for MEN1611 in combination with trastuzumab in HER2‐positive advanced or metastatic breast cancer patients

3. Mixed effects modeling of radiotherapy in combination with immune checkpoint blockade or inhibitors of the DNA damage response pathway

4. PK/PD model‐informed dose selection for oncology phase I expansion: Case study based on PF‐06939999, a PRMT5 inhibitor

5. Sabatolimab (MBG453) model‐informed drug development for dose selection in patients with myelodysplastic syndrome/acute myeloid leukemia and solid tumors

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Dosage Optimization: A Regulatory Perspective for Developing Oncology Drugs;Clinical Pharmacology & Therapeutics;2024-07-29