Nickel(II)-assisted enantiomeric differentiation and quantitation of tadalafil by direct electrospray ionization mass spectrometry
Author:
Affiliation:
1. Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences; Zhejiang University; Hangzhou 310058 China
2. Zhejiang Province Key Laboratory of Anti-Cancer Drug Research; Zhejiang University; Hangzhou 310058 China
Funder
National Natural Science Foundation of China
Publisher
Wiley
Subject
Spectroscopy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jms.3939/fullpdf
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2. Ventura J FDA approves Cialis to treat benign prostatic hyperplasia 2011 http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm274642.htm
3. Anti-inflammatory and cardioprotective effects of tadalafil in diabetic mice;Varma;PLoS One,2012
4. Chronic treatment with the long acting phosphodiesterase-5 inhibitor, tadalafil, decreases mitochondrial damage in diabetic mice;Aluri;Mitochondrion,2012
5. Tadalafil crosses the blood-brain barrier and reverses cognitive dysfunction in a mouse model of AD;Garciabarroso;Neuropharmacology,2013
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