Structure and characterization of Tremella fuciformis polysaccharides/whey protein isolate nanoparticles for sustained release of curcumin

Author:

Shang Jiaqi1,Liu Yang2,Kang Jiaxin3,Yang Shen4ORCID,Jin Ritian4ORCID

Affiliation:

1. Key Laboratory of Bionic Engineering, College of Biological and Agricultural Engineering Jilin University Changchun China

2. School of Physics and Electronic Engineering Northeast Petroleum University Daqing China

3. College of Food and Biological Engineering Qiqihar University Qiqihar China

4. College of Ocean Food and Biological Engineering Jimei University Xiamen China

Abstract

AbstractBACKGROUNDWhey protein isolate (WPI) nanoparticles can be used in a strategy to improve the bioavailability of curcumin (CUR) although they are generally not stable. Previous studies have indicated that Tremella fuciformis polysaccharides (TFPs) can increase the stability of WPI. This work investigated systematically the characterization and structure of TFP/WPI nanoparticles with differing CUR content.RESULTSThe highest encapsulation efficiency of CUR was 98.8% and the highest loading content was 47.88%. The TFP‐WPI‐CUR with 20 mg mL−1 of CUR had the largest particle size (653.67 ± 21.50 nm) and lowest zeta potential (−38.97 ± 2.51 mV), and the capacity to retain stability across a variety of salt ion and pH conditions for 21 days. According to the findings of the structural analysis, the addition of TFPs and CUR rendered the structure of WPI amorphous, and the β‐sheet was reduced. Finally, in vitro release indicated that the TFP‐WPI‐CUR combination could regulate the sustained release behavior of CUR.CONCLUSIONIn summary, TFP‐WPI nanoparticles can be used as carriers for the delivery of CUR, and can expand applications of CUR in the functional food, dietary supplement, pharmaceutical, and beverage industries. © 2023 Society of Chemical Industry.

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Nutrition and Dietetics,Agronomy and Crop Science,Food Science,Biotechnology

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3