Design and development of novel N ‐(4‐aminobenzoyl)‐ l ‐glutamic acid conjugated 1,3,5‐triazine derivatives as Pf ‐DHFR inhibitor: An in‐silico and in‐vitro study

Author:

Adhikari Nayana1,Choudhury Ayesha A. K.1,Shakya Anshul1,Ghosh Surajit K.1,Patgiri Saurav J.2,Singh Udaya P.3ORCID,Bhat Hans R.1ORCID

Affiliation:

1. Department of Pharmaceutical Sciences Dibrugarh University Dibrugarh Assam India

2. Regional Medical Research Centre, Indian Council of Medical Research (ICMR) Dibrugarh Assam India

3. Drug Design & Discovery Laboratory, Department of Pharmaceutical Sciences Sam Higginbottom University of Agriculture, Technology & Sciences Prayagraj Uttar Pradesh India

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Toxicology,Molecular Biology,Molecular Medicine,Biochemistry,General Medicine

Reference30 articles.

1. Drug-resistant malaria

2. In silico screening against wild-type and mutant Plasmodium falciparum dihydrofolate reductase

3. World Malaria Report2020.https://www.who.int/teams/global-malaria-programme/reports/world-malaria-report-2020

4. World malaria report2019.https://www.who.int/publications/i/item/9789241565721

5. The public health impact of chloroquine resistance in Africa

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