Baicalein is a novel TLR4‐targeting therapeutics agent that inhibits TLR4/HIF‐1α/VEGF signaling pathway in colorectal cancer-Reference-Cited by-同舟云学术

Baicalein is a novel TLR4‐targeting therapeutics agent that inhibits TLR4/HIF‐1α/VEGF signaling pathway in colorectal cancer

Published:2021-11 Issue:11 Volume:11 Page:
ISSN:2001-1326
Container-title:Clinical and Translational Medicine
language:en
Short-container-title:Clinical and Translational Medicine

Author:

Chen Minting¹,Zhong Keying²,Tan Jincheng²,Meng Mingjing²,Liu Chok Mei¹,Chen Baisen¹,Huang Chunhua¹,Wong Hoi Leong Xavier¹,Bian Zhaoxiang¹,Su Tao²,Kwan Hiu Yee¹^ORCID

Affiliation:

1. Centre for Cancer and Inflammation Research, School of Chinese Medicine Hong Kong Baptist University Hong Kong China

2. International Institute for Translational Chinese Medicine Guangzhou University of Chinese Medicine Guangzhou Guangdong China

Funder

Innovation and Technology Commission

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ctm2.564

Reference10 articles.

1. Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

2. Multiple Roles of Toll-Like Receptor 4 in Colorectal Cancer

3. Expression of HIF-1alpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implications

4. Clinicopathological Significances of Tumor–Stroma Ratio (TSR) in Colorectal Cancers: Prognostic Implication of TSR Compared to Hypoxia-Inducible Factor-1α Expression and Microvessel Density

5. ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

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