Comparison of Alternative Methods for Bioaccumulation Assessment: Scope and Limitations of In Vitro Depletion Assays with Rainbow Trout and Bioconcentration Tests in the Freshwater Amphipod Hyalella azteca-Reference-Cited by-同舟云学术

Comparison of Alternative Methods for Bioaccumulation Assessment: Scope and Limitations of In Vitro Depletion Assays with Rainbow Trout and Bioconcentration Tests in the Freshwater Amphipod Hyalella azteca

Published:2020-07-09 Issue:9 Volume:39 Page:1813-1825
ISSN:0730-7268
Container-title:Environmental Toxicology and Chemistry
language:en
Short-container-title:Environ Toxicol Chem

Author:

Kosfeld Verena¹²^ORCID,Fu Qiuguo³^ORCID,Ebersbach Ina¹,Esser Dana¹,Schauerte Anna¹,Bischof Ina¹,Hollender Juliane³⁴,Schlechtriem Christian¹²⁵^ORCID

Affiliation:

1. Department Bioaccumulation and Animal MetabolismFraunhofer Institute for Molecular Biology and Applied EcologySchmallenberg Germany

2. Institute for Environmental Research (Biology V)RWTH Aachen UniversityAachen Germany

3. Department Environmental ChemistryEawag, Swiss Federal Institute of Aquatic Science and Technology Dübendorf Switzerland

4. Institute of Biogeochemistry and Pollutant DynamicsETH ZürichZürich Switzerland

5. Department Chemistry and Biology“Ecotoxicology” Work Group, University of SiegenSiegen Germany

Funder

European Chemical Industry Council

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Environmental Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.4791

Reference50 articles.

1. Pharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance

2. Hepatocytes as in vitro test system to investigate metabolite patterns of pesticides in farmed rainbow trout and common carp: Comparison between in vivo and in vitro and across species

3. Comparative pharmaceutical metabolism by rainbow trout (Oncorhynchus mykiss) liver S9 fractions

4. Approach for extrapolating in vitro metabolism data to refine bioconcentration factor estimates

5. Animal use replacement, reduction, and refinement: Development of an integrated testing strategy for bioconcentration of chemicals in fish

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