Inhibition of iron uptake by ferristatin II is exerted through internalization of DMT1 at the plasma membrane

Author:

Yanatori Izumi1,Yasui Yumiko1,Noguchi Yumiko1,Kishi Fumio1

Affiliation:

1. Department of Molecular Genetics; Kawasaki Medical School; 577 Matsushima; Kurashiki Okayama 701-0192 Japan

Publisher

Wiley

Subject

Cell Biology,General Medicine

Reference32 articles.

1. Iron transport and storage proteins;Aisen;Annu Rev Biochem,1980

2. Identification of small molecule inhibitors that distinguish between non-transferrin bound iron uptake and transferrin-mediated iron transport;Brown;Chem Biol,2004

3. Small molecule inhibitors of divalent metal transporter-1;Buckett;Am J Physiol Gastrointest Liver Physiol,2009

4. Ferristatin II promotes degradation of transferrin receptor-1 in vitro and in vivo;Byrne;PLoS One,2013a

5. The iron transport inhibitor ferristatin II induces degradation of transferrin receptor-1;Byrne;FASEB J,2013b

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