Prostate cancer extracellular vesicles mediate intercellular communication with bone marrow cells and promote metastasis in a cholesterol‐dependent manner

Author:

Henrich Stephen E.12,McMahon Kaylin M.12,Plebanek Michael P.12,Calvert Andrea E.12,Feliciano Timothy J.12,Parrish Samuel1,Tavora Fabio3,Mega Anthony45,De Souza Andre45,Carneiro Benedito A.45,Thaxton C. Shad126

Affiliation:

1. Department of Urology Feinberg School of Medicine Northwestern University Chicago Illinois USA

2. Simpson Querrey Institute for BioNanotechnology Northwestern University Chicago Illinois USA

3. Department of Pathology Messejana Heart and Lung Hospital Fortaleza Brazil

4. Warren Alpert Medical School Brown University Providence Rhode Island USA

5. Lifespan Cancer Institute Providence Rhode Island USA

6. Robert H. Lurie Comprehensive Cancer Center Northwestern University Chicago Illinois USA

Funder

Prostate Cancer Foundation

National Cancer Institute

Publisher

Wiley

Subject

Cell Biology,Histology

Reference61 articles.

1. CYP27A1 Loss dysregulates cholesterol homeostasis in prostate cancer;Alfaqih M. A.;Cancer Research,2017

2. Circulating Tumor Cells and Bone Marrow Micrometastasis

3. Spatial organization of transmembrane receptor signalling

4. Bone marrow micrometastasis and circulating tumor cells are respectively strong prognostic factors in early and metastatic breast cancer, a comparative study on 759 patients;Bidard F. C.;Breast Cancer Research and Treatment,2007

5. Metastatic patterns of prostate cancer: An autopsy study of 1,589 patients

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