Affiliation:
1. Obstetrics and Gynecology Unit ASST Spedali Civili Brescia Italy
2. Respiratory Medicine Unit ASST Spedali Civili Brescia Italy
3. Department of Clinical and Experimental Sciences University of Brescia Brescia Italy
Abstract
AbstractObjectiveTo investigate pathological associations between sleep‐disordered breathing (SDB) and pregnancy outcomes.MethodsFrom May 2016 to September 2019, obese women during their uncomplicated singleton pregnancies underwent screening sleep questionnaires, oxygen saturation monitoring, and, in proper cases, complete overnight polysomnography. Their medical records were also recorded.ResultsIn all, 112 pregnant women were included in the study cohort; 44 showed an oxygen desaturation index ≥10, and their newborns had a significantly higher rate of congenital abnormalities and respiratory distress syndrome compared with the women with normal pulse oximetry. Stepwise multivariate regression analysis showed that basal oxygen saturation was independently associated with the occurrence of fetal growth restriction.ConclusionAmong obese pregnant women, the rate of congenital abnormalities is higher in the ones with altered pulse oximetry. Maternal basal oxygen saturation in the first trimester of pregnancy predicts fetal growth restriction independently of maternal age, ethnicity, body mass index, gravidity, and hypertensive disorders of pregnancy.
Subject
Obstetrics and Gynecology,General Medicine
Cited by
2 articles.
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